Faktor IX

F9
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 1CFH, 1CFI, 1EDM, 1IXA, 1MGX, 1NL0, 1RFN, 2WPH, 2WPI, 2WPJ, 2WPK, 2WPL, 2WPM, 3KCG, 3LC3, 3LC5, 4YZU, 4Z0K, 4ZAE, 4WM0, 4WMA, 4WMI, 4WMK, 4WN2, 4WNH, 5EGM, 5JBC, 5JB9, 5JBB, 5JB8, 5JBA
Identifikatori
Aliasi	F9
Vanjski ID-jevi	OMIM: 300746 MGI: 88384 HomoloGene: 106 GeneCards: F9
Lokacija gena (čovjek) Hrom. Hromosom X[1] Bend Xq27.1 Početak 139,530,739 bp[1] Kraj 139,563,459 bp[1]
Lokacija gena (miš) Hrom. Hromosom X (miš)[2] Bend X A6|X 33.5 cM Početak 59,044,824 bp[2] Kraj 59,076,119 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • endopeptidase activity • vezivanje iona metala • GO:0070122 peptidase activity • serine-type peptidase activity • hydrolase activity • calcium ion binding • serine-type endopeptidase activity • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • endoplasmic reticulum lumen • ćelijska membrana • Golgi lumen • Egzosom • extracellular region • Vanćelijsko • collagen-containing extracellular matrix Biološki proces • Hemostaza • blood coagulation, intrinsic pathway • zymogen activation • endoplasmic reticulum to Golgi vesicle-mediated transport • signal peptide processing • blood coagulation, extrinsic pathway • peptidyl-glutamic acid carboxylation • Proteoliza • Koagulacija (krv) Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	2158	14071
Ensembl	ENSG00000101981	ENSMUSG00000031138
UniProt	P00740	P16294
RefSeq (mRNK)	NM_000133 NM_001313913	NM_007979 NM_001305797
RefSeq (bjelančevina)	NP_000124 NP_001300842	NP_001292726 NP_032005
Lokacija (UCSC)	Chr X: 139.53 – 139.56 Mb	Chr X: 59.04 – 59.08 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Faktor IX ili Christmasov faktor (EC 3.4.21.22) je jedan od serinskih proteaza sistema koagulacije; pripada porodici peptidaza S1. Nedostatak ovog proteina uzrokuje hemofiliju B. Otkriven je 1952. godine nakon što je ustanovljeno da dječaku po imenu Stephen Christmas nedostaje pravilan ovaj faktor, što je dovelo do hemofilije.^[5]

1. ^ ^{a b c} GRCh38: Ensembl release 89: ENSG00000101981 - Ensembl, maj 2017
2. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000031138 - Ensembl, maj 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Biggs R, Douglas AS, Macfarlane RG, Dacie JV, Pitney WR (Dec 1952). "Christmas disease: a condition previously mistaken for haemophilia". British Medical Journal. 2 (4799): 1378–82. doi:10.1136/bmj.2.4799.1378. PMC 2022306. PMID 12997790.