ALK

ALK
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2KUP, 2KUQ, 2XB7, 2XBA, 2XP2, 2YFX, 2YHV, 2YJR, 2YJS, 2YS5, 2YT2, 3AOX, 3L9P, 3LCS, 3LCT, 4ANL, 4ANQ, 4ANS, 4CCB, 4CCU, 4CD0, 4CLI, 4CLJ, 4CMO, 4CMT, 4CMU, 4CNH, 4CTB, 4CTC, 4DCE, 4FNW, 4FNX, 4FNY, 4FNZ, 4FOB, 4FOD, 4JOA, 4MKC, 4TT7, 4Z55, 5FTO, 5AAB, 5AAA, 5J7H, 5AA9, 5IUH, 5IUI, 5IMX, 5FTQ, 5A9U, 5IUG, 5AA8, 5AAC
Dynodwyr
Cyfenwau	ALK, CD246, NBLST3, anaplastic lymphoma receptor tyrosine kinase, ALK receptor tyrosine kinase, ALK (gene), ALK1
Dynodwyr allanol	OMIM: 105590 HomoloGene: 68387 GeneCards: ALK
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • kinase activity • NF-kappaB-inducing kinase activity • GO:0001948, GO:0016582 protein binding • identical protein binding • ATP binding • transmembrane receptor protein tyrosine kinase activity • protein tyrosine kinase activity Cydrannau o'r gell • integral component of membrane • bilen • extracellular exosome • integral component of plasma membrane • intracellular anatomical structure • Cellbilen • GO:0009327 protein-containing complex • receptor complex Prosesau biolegol • regulation of apoptotic process • transmembrane receptor protein tyrosine kinase signaling pathway • nervous system development • protein phosphorylation • positive regulation of NF-kappaB transcription factor activity • cell population proliferation • protein autophosphorylation • GO:0072468 signal transduction • neuron development • peptidyl-tyrosine phosphorylation • NIK/NF-kappaB signaling • phosphorylation • brain development • hippocampus development • adult behavior • swimming behavior • regulation of cell population proliferation • regulation of dopamine receptor signaling pathway • response to environmental enrichment • regulation of neuron differentiation • positive regulation of dendrite development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	238	n/a
Ensembl	ENSG00000171094	n/a
UniProt	Q9UM73	n/a
RefSeq (mRNA)	NM_004304 NM_001353765	n/a
RefSeq (protein)	NP_004295 NP_001340694	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ALK yw ALK a elwir hefyd yn ALK receptor tyrosine kinase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p23.2-p23.1.^[2]

1. ↑ "Human PubMed Reference:".
2. ↑ ALK - Cronfa NCBI