INSR

INSR
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1GAG, 1I44, 1IR3, 1IRK, 1P14, 1RQQ, 2AUH, 2B4S, 2HR7, 3BU3, 3BU5, 3BU6, 3EKK, 3EKN, 3ETA, 3W11, 3W12, 3W13, 3W14, 2MFR, 2Z8C, 4IBM, 4OGA, 4XLV, 4XST, 5E1S, 4ZXB, 5J3H, 5HHW
Dynodwyr
Cyfenwau	INSR, CD220, HHF5, insulin receptor
Dynodwyr allanol	OMIM: 147670 HomoloGene: 20090 GeneCards: INSR
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• kinase activity; • insulin-like growth factor II binding; • transmembrane receptor protein tyrosine kinase activity; • ATP binding; • protein kinase activity; • insulin-like growth factor receptor binding; • insulin receptor substrate binding; • transferase activity; • GO:0001948, GO:0016582 protein binding; • protein tyrosine kinase activity; • nucleotide binding; • insulin-like growth factor I binding; • GTP binding; • PTB domain binding; • phosphatidylinositol 3-kinase binding; • insulin binding; • insulin-activated receptor activity; • protein domain specific binding; • amyloid-beta binding; • cargo receptor activity; • GO:0032403 protein-containing complex binding;
Cydrannau o'r gell	• bilen; • caveola; • insulin receptor complex; • extracellular exosome; • integral component of membrane; • receptor complex; • Cellbilen; • endosome membrane; • integral component of plasma membrane; • intracellular anatomical structure; • nuclear envelope; • external side of plasma membrane; • axon; • nuclear lumen; • dendrite membrane; • neuronal cell body membrane;
Prosesau biolegol	• positive regulation of glucose import; • GO:1901047 insulin receptor signaling pathway; • positive regulation of protein phosphorylation; • regulation of embryonic development; • positive regulation of developmental growth; • protein phosphorylation; • regulation of female gonad development; • animal organ morphogenesis; • transformation of host cell by virus; • positive regulation of mitotic nuclear division; • positive regulation of meiotic cell cycle; • positive regulation of protein kinase B signaling; • positive regulation of glycogen biosynthetic process; • GO:0009373 regulation of transcription, DNA-templated; • transmembrane receptor protein tyrosine kinase signaling pathway; • male sex determination; • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated; • epidermis development; • cellular response to insulin stimulus; • protein autophosphorylation; • positive regulation of respiratory burst; • positive regulation of MAPK cascade; • exocrine pancreas development; • G protein-coupled receptor signaling pathway; • male gonad development; • phosphorylation; • carbohydrate metabolic process; • positive regulation of DNA replication; • peptidyl-tyrosine autophosphorylation; • activation of protein kinase B activity; • positive regulation of cell migration; • positive regulation of nitric oxide biosynthetic process; • cellular response to growth factor stimulus; • heart morphogenesis; • adrenal gland development; • positive regulation of cell population proliferation; • positive regulation of glycolytic process; • activation of protein kinase activity; • GO:0072468 signal transduction; • glucose homeostasis; • peptidyl-tyrosine phosphorylation; • protein heterotetramerization; • GO:0007243 intracellular signal transduction; • receptor-mediated endocytosis; • learning; • Cof; • positive regulation of phosphatidylinositol 3-kinase signaling; • positive regulation of protein-containing complex disassembly; • GO:1903374 anatomical structure development; • dendritic spine maintenance; • amyloid-beta clearance; • neuron projection maintenance;
	Sources:Amigo / QuickGO
Orthologau
	3643
	n/a
	ENSG00000171105
	n/a
	P06213
	n/a
	NM_000208; NM_001079817
	n/a
	NP_000199; NP_001073285
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn INSR yw INSR a elwir hefyd yn Insulin receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.2.^[2]

[1] "Human PubMed Reference:".

[2] INSR - Cronfa NCBI

[1]

[2]

INSR

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