SRF

SRF
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1HBX, 1K6O, 1SRS
Dynodwyr
Cyfenwau	SRF, MCM1, serum response factor
Dynodwyr allanol	OMIM: 600589 HomoloGene: 31135 GeneCards: SRF
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein dimerization activity • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0000983 RNA polymerase II general transcription initiation factor activity • primary miRNA binding • transcription factor binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • protein homodimerization activity • serum response element binding • chromatin binding • GO:0001948, GO:0016582 protein binding • DNA binding • sequence-specific DNA binding • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • chromatin DNA binding • transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding • GO:0001158 cis-regulatory region sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • histone deacetylase binding • RNA polymerase II-specific DNA-binding transcription factor binding Cydrannau o'r gell • cytoplasm • cnewyllyn cell • nucleoplasm Prosesau biolegol • dorsal aorta morphogenesis • bronchus cartilage development • muscle cell cellular homeostasis • lung smooth muscle development • regulation of water loss via skin • transcription by RNA polymerase II • stress fiber assembly • cell migration involved in sprouting angiogenesis • platelet activation • cardiac myofibril assembly • heart looping • cellular senescence • face development • regulation of cell adhesion • long-term depression • neuron projection development • morphogenesis of an epithelial sheet • positive regulation of filopodium assembly • primitive streak formation • cellular response to glucose stimulus • negative regulation of cell population proliferation • response to cytokine • GO:0009373 regulation of transcription, DNA-templated • heart trabecula formation • actin filament organization • thymus development • angiogenesis involved in wound healing • platelet formation • neuron development • in utero embryonic development • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • heart development • positive regulation of cell differentiation • branching involved in blood vessel morphogenesis • positive regulation of axon extension • positive regulation of smooth muscle contraction • trachea cartilage development • response to toxic substance • positive regulation of pri-miRNA transcription by RNA polymerase II • positive regulation of transcription by glucose • regulation of smooth muscle cell differentiation • epithelial structure maintenance • associative learning • skin morphogenesis • positive regulation of DNA-binding transcription factor activity • epithelial cell-cell adhesion • neuron migration • positive regulation of transcription initiation from RNA polymerase II promoter • eyelid development in camera-type eye • thyroid gland development • negative regulation of amyloid-beta clearance • negative regulation of cell migration • developmental growth • hematopoietic stem cell differentiation • gastrulation • trophectodermal cell differentiation • positive thymic T cell selection • response to hormone • cell-matrix adhesion • sarcomere organization • actin cytoskeleton organization • megakaryocyte development • response to hypoxia • lung morphogenesis • mesoderm formation • cardiac vascular smooth muscle cell differentiation • mRNA transcription by RNA polymerase II • multicellular organism development • tangential migration from the subventricular zone to the olfactory bulb • long-term memory • contractile actin filament bundle assembly • bicellular tight junction assembly • leukocyte differentiation • hippocampus development • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • erythrocyte development • negative regulation of pri-miRNA transcription by RNA polymerase II • forebrain development • cell-cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6722	n/a
Ensembl	ENSG00000112658	n/a
UniProt	P11831	n/a
RefSeq (mRNA)	NM_003131 NM_001292001	n/a
RefSeq (protein)	NP_001278930 NP_003122 NP_003122.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SRF yw SRF a elwir hefyd yn Serum response factor a Serum response factor (C-fos serum response element-binding transcription factor), isoform CRA_a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p21.1.^[2]

1. ↑ "Human PubMed Reference:".
2. ↑ SRF - Cronfa NCBI