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Homology-directed Repair

Mechanismen der Homologie-gerichteten Reparatur[1]

Homology-directed Repair (‚Homologie-gerichtete Reparatur‘, HDR) bezeichnet einen Mechanismus der DNA-Reparatur von DNA-Schäden, welcher per homologer Rekombination Doppelstrangbrüche von DNA repariert.

  1. ↑ C. Gelot, I. Magdalou, B. S. Lopez: Replication stress in Mammalian cells and its consequences for mitosis. In: Genes. Band 6, Nummer 2, Mai 2015, S. 267–298, doi:10.3390/genes6020267, PMID 26010955, PMC 4488665 (freier Volltext).
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