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AEL may refer to:
- Acute eosinophilic leukemia, a form of leukemia
- AEL Limassol (Athlitiki Enosi Limassol), a Cypriot sports club, most known for its football section
- AEL Limassol B.C., a Cypriot basketball club
- AEL (motorcycle), an early-20th century motorcycle maker in Coventry, England
- African Explosives, a mining services company headquartered in Johannesburg
- Ambele language of Cameroon, ISO 639-3 code ael
- American Electronics Laboratories, former parent of Mooney International Corporation
- Arab European League, in Belgium and the Netherlands
- Asiatic Exclusion League, in the US and Canada
- Association Electronique Libre
- Athletic Union of Larissa (Athlitiki Enosi Larissa 1964), Greek sports club
- A.E.L. 1964 B.C., AE Larissa GS, Greek professional basketball club
- Athlitiki Enosi Larissa F.C., or Larissa, a Greek football club
- Authorized Equipment List, items eligible for the Homeland Security Grant Program