In eukaryotic cells, an aggresome refers to an aggregation of misfolded proteins in the cell, formed when the protein degradation system of the cell is overwhelmed. Aggresome formation is a highly regulated process that possibly serves to organize misfolded proteins into a single location.[1]
- ^ Corboy MJ, Thomas PJ, Wigley WC (2005). "Aggresome formation". Ubiquitin-Proteasome Protocols. Methods Mol. Biol. Vol. 301. pp. 305–27. doi:10.1385/1-59259-895-1:305. ISBN 978-1-59259-895-3. PMID 15917642.