Almestrone

Almestrone
Clinical data
Other names	Ba 38372; Ciba 38372; 7α-Methylestrone
Routes of; administration	By mouth
Drug class	Estrogen
ATC code	None;
Identifiers
	IUPAC name (7R,8R,9S,13S,14S)-3-hydroxy-7,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one;
CAS Number	10448-96-1;
PubChem CID	65601;
ChemSpider	59042;
UNII	N18A31MTB0;
ChEMBL	ChEMBL2104052;
CompTox Dashboard (EPA)	DTXSID001016949 ;
ECHA InfoCard	100.212.018
Chemical and physical data
Formula	C19H24O2
Molar mass	284.399 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1CC2=C(C=CC(=C2)O)C3C1C4CCC(=O)C4(CC3)C;
	InChI InChI=InChI=1S/C19H24O2/c1-11-9-12-10-13(20)3-4-14(12)15-7-8-19(2)16(18(11)15)5-6-17(19)21/h3-4,10-11,15-16,18,20H,5-9H2,1-2H3/t11-,15-,16+,18-,19+/m1/s1; Key:JUAJXSMWFOFDFC-MNHDCVOLSA-N;

Almestrone (INNTooltip International Nonproprietary Name) (developmental code names Ba 38372, Ciba 38372), also known as 7α-methylestrone, is a synthetic, steroidal estrogen which was synthesized in 1967 but was never marketed.^[1] It is used as a precursor in the synthesis of several highly active steroids.^[2]^[3]

^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 900–. ISBN 978-1-4757-2085-3.
^ Krause N, Aksin-Artok Ö (2011). "Copper-Mediated and Copper-Catalyzed Addition and Substitution Reactions of Extended Multiple Bond Systems". PATai's Chemistry of Functional Groups. doi:10.1002/9780470682531.pat0450. ISBN 9780470682531.
^ Morais GR, Yoshioka N, Watanabe M, Mataka S, Oliveira CD, Thiemann T (2006). "C7-Substituted Estranes and Related Steroids". Mini-Reviews in Organic Chemistry. 3 (3): 229–251. doi:10.2174/1570193X10603030229. ISSN 1570-193X.

[Elks2014-1] Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 900–. ISBN 978-1-4757-2085-3.

[KrauseAksin-Artok2011-2] Krause N, Aksin-Artok Ö (2011). "Copper-Mediated and Copper-Catalyzed Addition and Substitution Reactions of Extended Multiple Bond Systems". PATai's Chemistry of Functional Groups. doi:10.1002/9780470682531.pat0450. ISBN 9780470682531.

[Ribeiro_MoraisYoshioka2006-3] Morais GR, Yoshioka N, Watanabe M, Mataka S, Oliveira CD, Thiemann T (2006). "C7-Substituted Estranes and Related Steroids". Mini-Reviews in Organic Chemistry. 3 (3): 229–251. doi:10.2174/1570193X10603030229. ISSN 1570-193X.

[1]

[2]

[3]

Clinical data

Other names	Ba 38372; Ciba 38372; 7α-Methylestrone
Routes of administration	By mouth
Drug class	Estrogen
ATC code	None
Identifiers
IUPAC name (7R,8R,9S,13S,14S)-3-hydroxy-7,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
CAS Number	10448-96-1
PubChem CID	65601
ChemSpider	59042
UNII	N18A31MTB0
ChEMBL	ChEMBL2104052
CompTox Dashboard (EPA)	DTXSID001016949
ECHA InfoCard	100.212.018
Chemical and physical data
Formula	C₁₉H₂₄O₂
Molar mass	284.399 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC1CC2=C(C=CC(=C2)O)C3C1C4CCC(=O)C4(CC3)C
InChI InChI=InChI=1S/C19H24O2/c1-11-9-12-10-13(20)3-4-14(12)15-7-8-19(2)16(18(11)15)5-6-17(19)21/h3-4,10-11,15-16,18,20H,5-9H2,1-2H3/t11-,15-,16+,18-,19+/m1/s1 Key:JUAJXSMWFOFDFC-MNHDCVOLSA-N

Almestrone

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