Ampicillin/sulbactam

Ampicillin/sulbactam
Combination of
AmpicillinPenicillin antibiotic
SulbactamBeta-lactamase inhibitor
Clinical data
Pronunciationam pi sill' in and sul bak' tam
Trade namesUnasyn
AHFS/Drugs.comMonograph
MedlinePlusa693021
Routes of
administration
Intramuscular, intraveneous
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
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Ampicillin/sulbactam is a fixed-dose combination medication of the common penicillin-derived antibiotic ampicillin and sulbactam, an inhibitor of bacterial beta-lactamase. Two different forms of the drug exist. The first, developed in 1987 and marketed in the United States under the brand name Unasyn, generic only outside the United States, is an intravenous antibiotic. The second, an oral form called sultamicillin, is marketed under the brand name Ampictam outside the United States, and generic only in the United States. Ampicillin/sulbactam is used to treat infections caused by bacteria resistant to beta-lactam antibiotics. Sulbactam blocks the enzyme which breaks down ampicillin and thereby allows ampicillin to attack and kill the bacteria.

  1. ^ "Unasyn- ampicillin sodium and sulbactam sodium injection, powder, for solution". DailyMed. U.S. National Library of Medicine. 17 October 2019. Retrieved 12 October 2020.

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