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Names | |
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IUPAC names
trans-4,7-Dioxadispiro[4.0.46.25]dodeca-1,9-diene-3,8-dione
trans-1,7-Dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione[1] | |
Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C10H8O4 | |
Molar mass | 192.170 g·mol−1 |
Appearance | Colourless, odourless solid |
Density | 1.45g/cm3 |
Melting point | 158[1] °C (316 °F; 431 K) |
Boiling point | 535.7 °C (996.3 °F; 808.9 K) @ 760mmHg |
low | |
Solubility in chloroform | very soluble[1] |
Hazards | |
Flash point | 300.7 °C (573.3 °F; 573.8 K) |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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150 mg·kg−1 (mouse, IP) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Anemonin is a tri-spirocyclic dibutenolide natural product found in members of the buttercup family (Ranunculaceae) such as Ranunculus bulbosus, R. ficaria, R. sardous, R. sceleratus,[2] and Clematis hirsutissima.[3] Originally isolated in 1792 by M. Heyer,[4] It is the dimerization product of the toxin protoanemonin.[5] One of the likely active agents in plants used in Chinese medicine as an anti-inflammatory[6] and Native American medicine as a horse stimulant,[3] its unique biological properties give it pharmaceutical potential as an anti-inflammatory and cosmetic agent.