Antiserum

In immunology, antiserum is a blood serum containing antibodies (either monoclonal or polyclonal) that is used to spread passive immunity to many diseases via blood donation (plasmapheresis). For example, convalescent serum, passive antibody transfusion from a previous human survivor, used to be the only known effective treatment for ebola infection with a high success rate of 7 out of 8 patients surviving.[1]

Antisera are widely used in diagnostic virology laboratories. The most common use of antiserum in humans is as antitoxin or antivenom to treat envenomation.[citation needed]

Serum therapy, also known as serotherapy, describes the treatment of infectious diseases using the serum of animals that have been immunized against the specific organism or components of that organism.[2][3]

  1. ^ Mupapa, K; Massamba, M; Kibadi, K; Kuvula, K; Bwaka, A; Kipasa, M; Colebunders, R; Muyembe-Tamfum, JJ (1999). "Treatment of Ebola Hemorrhagic Fever with Blood Transfusions from Convalescent Patients". The Journal of Infectious Diseases. 179 Suppl 1 (179): S18 – S23. doi:10.1086/514298. PMID 9988160.
  2. ^ Young, Lowell S. (1 April 1984). "Immunoprophylaxis and serotherapy of bacterial infections". The American Journal of Medicine. 76 (4): 664–671. doi:10.1016/0002-9343(84)90292-4. ISSN 0002-9343. Retrieved 19 January 2025.
  3. ^ Erichson, Robert B. (December 1961). "SEROTHERAPY IN VIRUS DISEASES". The Lancet. 278 (7217): 1414. doi:10.1016/S0140-6736(61)91238-7. Retrieved 19 January 2025.

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