The arginine catabolic mobile element (ACME) is a mobile genetic element of Staphylococcus bacterial species. This genetic element provides for several immune modulating functions, including resistance to polyamines which serve as a non-specific immune response both on intact skin and following the inflammatory response in wound healing.[1][2] Diverse ACME are present in several species of Staphylococcus, including Staphylococcus epidermidis.[3][4]
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- ^ Barbier, F.; Lebeaux, D.; Hernandez, D.; Delannoy, A.-S.; Caro, V.; Francois, P.; Schrenzel, J.; Ruppe, E.; Gaillard, K.; Wolff, M.; Brisse, S.; Andremont, A.; Ruimy, R. (9 November 2010). "High prevalence of the arginine catabolic mobile element in carriage isolates of methicillin-resistant Staphylococcus epidermidis". Journal of Antimicrobial Chemotherapy. 66 (1): 29–36. doi:10.1093/jac/dkq410. PMID 21062794.
- ^ Miragaia, Maria; de Lencastre, Herminia; Perdreau-Remington, Francoise; Chambers, Henry F.; Higashi, Julie; Sullam, Paul M.; Lin, Jessica; Wong, Kester I.; King, Katherine A.; Otto, Michael; Sensabaugh, George F.; Diep, Binh An; DeLeo, Frank R. (6 November 2009). "Genetic Diversity of Arginine Catabolic Mobile Element in Staphylococcus epidermidis". PLOS ONE. 4 (11): e7722. Bibcode:2009PLoSO...4.7722M. doi:10.1371/journal.pone.0007722. PMC 2768820. PMID 19893740.