Bromopride

Bromopride
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral, IM, IV
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability50 to 75% (oral)
78% (intramuscular)
Protein binding40%
MetabolismHepatic
Elimination half-life4 to 5 hours
ExcretionRenal, 10 to 14% unchanged
Identifiers
  • 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.021.675 Edit this at Wikidata
Chemical and physical data
FormulaC14H22BrN3O2
Molar mass344.253 g·mol−1
3D model (JSmol)
  • Brc1cc(c(OC)cc1N)C(=O)NCCN(CC)CC
  • InChI=1S/C14H22BrN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) checkY
  • Key:GIYAQDDTCWHPPL-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Bromopride (INN) is a dopamine antagonist with prokinetic properties widely used as an antiemetic, closely related to metoclopramide. It is not available in the United States.

Bromopride appears to be safe and effective for use in pregnancy.[1]

  1. ^ Araújo JR (1981). "Evaluation of bromopride in nausea and vomiting of pregnancy". J Bras Ginecol (in Portuguese). 91 (4): 283–5.

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