Bryan Station (also Bryan's Station, and often misspelled Bryant's Station) was an early fortified settlement in Lexington, Kentucky. It was located on present-day Bryan Station Road, about three miles (5 km) northeast of New Circle Road, on the southern bank of Elkhorn Creek near Briar Hill Road. The settlement was established in the spring of 1776 by brothers Morgan, James, William (married to Mary Boone, sister of Daniel Boone), and Joseph Bryan, and brother-in-law William Grant (married to Elizabeth Jane "Betsy" Boone, also a sister of Daniel Boone), all from Yadkin River Valley, Rowan County, North Carolina.[5] After a disastrous winter and attacks by Native Americans, all the Bryan family survivors abandoned the station and returned to the Yadkin River Valley in August 1780.[6] Falling under the command of Elijah Craig,[7] the remaining occupants withstood several American Indian attacks.