In neuroscience, the chemoaffinity hypothesis states that neurons make connections with their targets based on interactions with specific molecular markers[1][unreliable source?] and, therefore, that the initial wiring diagram of an organism is (indirectly) determined by its genotype. The markers are generated during cellular differentiation and aid not only with synaptogenesis, but also act as guidance cues for their respective axon.[1]
- ^ a b "BIO254:Chemoaffinity". OpenWetWare. Retrieved 1 September 2011.