Back سيكلوبيروكس Arabic Ciclopirocs Olamin Welsh Ciclopirox German Ciclopirox Spanish سیکلوپیروکس Persian Ciclopirox French ציקלופירוקס HE Ciklopirox Hungarian Ciclopiroxolamina Italian シクロピロクス Japanese

Ciclopirox

Ciclopirox
Clinical data
Trade namesPenlac Nail Lacquer, others[1]
Other namesLoprox, CPX
AHFS/Drugs.comMonograph
MedlinePlusa604021
License data
Routes of
administration		Topical
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability<5% with prolonged use
Protein binding94 to 97%
Elimination half-life1.7 hours
Identifiers
  • 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.045.056 Edit this at Wikidata
Chemical and physical data
FormulaC12H17NO2
Molar mass207.273 g·mol−1
3D model (JSmol)
  • O=C1/C=C(\C=C(/N1O)C2CCCCC2)C
  • InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 checkY
  • Key:SCKYRAXSEDYPSA-UHFFFAOYSA-N checkY
  (verify)

Ciclopirox is a medication used for the treatment of moderate onychomycosis of fingernails and toenails,[3] and for the treatment of seborrheic dermatitis.[4]

In 2022, it was the 247th most commonly prescribed medication in the United States, with more than 1 million prescriptions.[5][6]

  1. ^ Cite error: The named reference brands was invoked but never defined (see the help page).
  2. ^ "Penlac Nail Lacquer (ciclopirox) Topical Solution, 8%". DailyMed. Retrieved 2 December 2024.
  3. ^ a b Cite error: The named reference Ciclodan FDA label was invoked but never defined (see the help page).
  4. ^ a b Cite error: The named reference Loprox FDA label was invoked but never defined (see the help page).
  5. ^ "The Top 300 of 2022". ClinCalc. Archived from the original on 30 August 2024. Retrieved 30 August 2024.
  6. ^ "Ciclopirox Drug Usage Statistics, United States, 2013 - 2022". ClinCalc. Retrieved 30 August 2024.
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