Mary Clare de Graffenried (May 19, 1849 – April 26, 1921) was an American labor researcher and writer, who worked as an investigator for the U.S. Department of Labor beginning in 1888. She wrote a number of influential articles on the conditions of working-class people, particularly women and children, including the controversial 1891 essay "The Georgia Cracker in the Cotton Mill." Her work is notable for its early inclusion of scientific data as a basis for rhetorical argument in discussions of the American working class.