Cyclopia | |
---|---|
Other names | Cyclocephaly, synophthalmia |
Fetuses with cyclopia | |
Specialty | Medical genetics |
Usual onset | During embryonic development |
Duration | Lifelong |
Prognosis | Almost always fatal within a day |
Frequency | 1 in 100,000 births |
Cyclopia (named after the Greek mythology characters cyclopes), also known as alobar holoprosencephaly, is the most extreme form of holoprosencephaly and is a congenital disorder (birth defect) characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities. Its incidence is 1 in 16,000 in born animals and 1 in 200 in miscarried fetuses.[1][2]