Eli Whitney (1765–1825) was an American inventor and entrepreneur, best known for his cotton gin and his pursuit of interchangeability in firearms manufacture.
Eli Whitney may also refer to:
- Eli Whitney Jr. (1820–1825), son of the inventor, maker of the Colt Walker revolver
- Eli Whitney Museum in the U.S. state of Connecticut
- Eli Whitney, North Carolina, an unincorporated community in the U.S. state of North Carolina