Elisabeth of Hesse (1539–1582) was the fourth daughter of Philip I, Landgrave of Hesse, and the first spouse of Louis VI, Elector Palatine.
Elisabeth of Hesse may also refer to:
- Elisabeth of Hesse-Marburg (1466–1523), eldest daughter of Henry III, Landgrave of Upper Hesse
- Elisabeth of Hesse, Hereditary Princess of Saxony (1502–1557), eldest daughter of William II, Landgrave of Hesse
- Elisabeth of Hesse, Countess Palatine of Zweibrücken (1503–1563), youngest daughter of William I, Landgrave of Lower Hesse
- Princess Elisabeth of Hesse and by Rhine (disambiguation), various princesses, including