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Epithelioid cell

Epithelioid cells formed in culture of mouse peritoneal cells, stimulated by inactivated Mycobacterium tuberculosis, in a micro-chamber for lifetime observation; 14 days of cultivating. Numerous secretory granules are visible in the cytoplasm of cells. In the culture medium epithelioid cell granules and apoptotic bodies from macrophage are visible. Dystrophic altered macrophages are colored red. A method of interferential contrast in polarized light.

Epithelioid cells (also called epithelioid histiocytes) are derivatives of activated macrophages resembling epithelial cells.[1][2][3]

  1. ^ "Epithelioid cell". Oxford Reference:epithelioid cell. Oxford University Press. January 2010. ISBN 978-0-19-953301-5.
  2. ^ Van Furth R, Cohn ZA, Hirsch JG, Humphrey JH, Spector WG, Langevoort HL (1972). "The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells". Bull World Health Organ. 46 (6): 845–52. PMC 2480884. PMID 4538544.
  3. ^ Ramakrishnan L (April 2012). "Revisiting the role of the granuloma in tuberculosis". Nat Rev Immunol. 12 (5): 352–66. doi:10.1038/nri3211. PMID 22517424. S2CID 1139969.
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