Family Affair (Grey's Anatomy)

"Family Affair"
Grey's Anatomy episode
Episode no.	Season 12 Episode 24
Directed by	Debbie Allen
Written by	William Harper
Original air date	May 19, 2016 (2016-05-19)
Running time	43 minutes
Guest appearances
Joe Adler as Dr. Isaac Cross Debra Mooney as Evelyn Hunt Barbara Montgomery as Louise
Episode chronology
← Previous "At Last" Next → "Undo"
Grey's Anatomy season 12
List of episodes

"Family Affair" is the twenty-fourth episode and the season finale of the twelfth season of the American medical drama television series Grey's Anatomy, and the 269th episode overall. Written by William Harper and directed by Debbie Allen, the episode aired on the American Broadcasting Company (ABC) in the United States on May 19, 2016.

The episode centers around the wedding of Owen Hunt (Kevin McKidd) and Amelia Shepherd (Caterina Scorsone), where tensions run high. Meredith Grey (Ellen Pompeo) and Maggie Pierce (Kelly McCreary) provide emotional support to Amelia on her big day. Meanwhile, Jo Wilson (Camilla Luddington) confesses a long-held secret to Alex Karev (Justin Chambers), while Arizona Robbins (Jessica Capshaw) and Callie Torres (Sara Ramirez) navigate the emotional aftermath of their custody battle. Ben Warren (Jason George) performs an emergency C-section on April Kepner (Sarah Drew) at Meredith's house, delivering April’s baby.

The episode marked the final appearance of longtime cast member Ramirez, who had been part of the series since Season 2. Ramirez announced their departure, stating they were "taking some welcome time off" as their character moved to New York with her daughter.

Upon its original broadcast, "Family Affair" was watched by 8.19 million viewers in the United States, ranking #2 in its time-slot, and earned a 2.3/9 Nielsen rating in the 18–49 demographic. The episode received positive reviews from critics, with praise directed towards the performances of Ramirez and Capshaw.