Sexual orientation |
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Sexual orientations |
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Fraternal birth order, also known as the older brother effect, has been correlated with male sexual orientation, with a significant volume of research finding that the more older brothers a male has from the same mother, the greater the probability he will have a homosexual orientation. Ray Blanchard and Anthony Bogaert first identified the association in the 1990s and named it the fraternal birth order effect. Scientists have attributed the effect to a prenatal biological mechanism, since the association is only present in men with older biological brothers, and not present among men with older step-brothers and adoptive brothers. The mechanism is thought to be a maternal immune response to male fetuses, whereby antibodies neutralize male Y-proteins thought to play a role in sexual differentiation during development. This would leave some regions of the brain associated with sexual orientation in the 'female typical' arrangement – or attracted to men.
The effect becomes stronger with each additional male pregnancy, with odds of the next son being homosexual increasing by 38–48%. This does not mean that all or most sons will be homosexual after several male pregnancies, but rather, the odds of having a homosexual son increase from approximately 2% for the first born son, to 3% for the second, 5% for the third and so on.[1][2] In a 2017 study; mothers with gay sons, particularly those with older brothers, had heightened levels of antibodies to the NLGN4Y Y-protein compared to mothers with heterosexual sons.[1][3]
It has generally been thought that this maternal response would not apply to first-born gay sons and that they may owe their orientation to other mechanisms.[3] However, mothers with no sons also showed antibodies to male cells, which may be a result of male miscarriages or abortion.[3][4]