Genetic history of Italy

Principal Component Analysis of the Italian population[1]

The genetic history of Italy includes information around the formation, ethnogenesis, and other DNA-specific information about the inhabitants of Italy. Modern Italians mostly descend from the ancient peoples of Italy, including Indo-European speakers (Romans and other Latins, Falisci, Picentes, Umbrians, Samnites, Oscans, Sicels, Elymians, Messapians and Adriatic Veneti, as well as Magno-Greeks, Cisalpine Gauls and Illyric Iapygians) and pre-Indo-European speakers (Etruscans, Ligures, Rhaetians Camunni, Sicani, Nuragic peoples), as well as settlers from Phoenicia and Carthage in Sardinia and in the westernmost part of Sicily. Other groups migrated into Italy as a result of the Roman Empire, when the Italian peninsula attracted people from the various regions of the empire (North Africa, West Asia and the rest of Europe),[2] and during the Middle Ages with the arrival of Ostrogoths, Longobards, Franks, Saracens and Normans among others. Based on DNA analysis, there is evidence of regional genetic substructure and continuity within modern Italy dating back to antiquity.[3][4][5][6]

In their admixture ratios, Italians are similar to other Southern Europeans, and that is being of primarily Neolithic Early European Farmer ancestry, along with smaller, but still significant, amounts of Mesolithic Western Hunter-Gatherer, Bronze Age Steppe pastoralist (Indo-European speakers) and Chalcolithic or Bronze Age Iranian/Caucasus-related ancestry.[4][7][8][9][10][4] According to multiple genome-wide studies Southern Italians are closest to modern Greeks,[11][12][13][14][15][16][17][18][19][10] while Northern Italians are closest to the Spaniards, the Portuguese and to a lesser extent people from Southern France.[11][18][20][21][22][17][23][24][25][26][19][27] There is also Bronze/Iron Age Anatolian admixture in Italy, with a much lower incidence in Northern Italy compared with Central Italy and Southern Italy.[24][8] Marginal levels (0.1-4%) of North African admixture is also found in Southern Italy with the highest incidence being in the islands of Sicily and Sardinia.[24][8][4]

  1. ^ Parolo S, Lisa A, Gentilini D, Di Blasio AM, Barlera S, Nicolis EB, et al. (November 2015). "Characterization of the biological processes shaping the genetic structure of the Italian population". BMC Genetics. 16: 132. doi:10.1186/s12863-015-0293-x (inactive 1 December 2024). PMC 4640365. PMID 26553317.{{cite journal}}: CS1 maint: DOI inactive as of December 2024 (link)
  2. ^ Cite error: The named reference Antonio_2019 was invoked but never defined (see the help page).
  3. ^ Ralph P, Coop G (2013). "The geography of recent genetic ancestry across Europe". PLOS Biology. 11 (5): e1001555. doi:10.1371/journal.pbio.1001555. PMC 3646727. PMID 23667324.
  4. ^ a b c d Raveane A, Aneli S, Montinaro F, Athanasiadis G, Barlera S, Birolo G, et al. (September 2019). "Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe". Science Advances. 5 (9): eaaw3492. Bibcode:2019SciA....5.3492R. doi:10.1126/sciadv.aaw3492. PMC 6726452. PMID 31517044.
  5. ^ Capocasa M, Anagnostou P, Bachis V, Battaggia C, Bertoncini S, Biondi G, et al. (2014). "Linguistic, geographic and genetic isolation: a collaborative study of Italian populations". Journal of Anthropological Sciences. 92 (92): 201–31. doi:10.4436/JASS.92001. PMID 24607994.
  6. ^ Modi A, Lancioni H, Cardinali I, Capodiferro MR, Rambaldi Migliore N, Hussein A, et al. (July 2020). "The mitogenome portrait of Umbria in Central Italy as depicted by contemporary inhabitants and pre-Roman remains". Scientific Reports. 10 (1): 10700. Bibcode:2020NatSR..1010700M. doi:10.1038/s41598-020-67445-0. PMC 7329865. PMID 32612271.
  7. ^ Cite error: The named reference Chiang_2018 was invoked but never defined (see the help page).
  8. ^ a b c Cite error: The named reference Marcus_2020 was invoked but never defined (see the help page).
  9. ^ Fernandes DM, Mittnik A, Olalde I, Lazaridis I, Cheronet O, Rohland N, et al. (March 2020). "The spread of steppe and Iranian-related ancestry in the islands of the western Mediterranean". Nature Ecology & Evolution. 4 (3): 334–345. Bibcode:2020NatEE...4..334F. doi:10.1038/s41559-020-1102-0. PMC 7080320. PMID 32094539.
  10. ^ a b Sarno, Stefania; Petrilli, Rosalba; Abondio, Paolo; De Giovanni, Andrea; Boattini, Alessio; Sazzini, Marco; De Fanti, Sara; Cilli, Elisabetta; Ciani, Graziella; Gentilini, Davide; Pettener, Davide; Romeo, Giovanni; Giuliani, Cristina; Luiselli, Donata (2021-02-04). "Genetic history of Calabrian Greeks reveals ancient events and long term isolation in the Aspromonte area of Southern Italy". Scientific Reports. 11 (1): 3045. doi:10.1038/s41598-021-82591-9. ISSN 2045-2322. PMC 7862261.
  11. ^ a b Novembre, John; Johnson, Toby; Bryc, Katarzyna; Kutalik, Zoltán; Boyko, Adam R.; Auton, Adam; Indap, Amit; King, Karen S.; Bergmann, Sven; Nelson, Matthew R.; Stephens, Matthew; Bustamante, Carlos D. (2008-08-31). "Genes mirror geography within Europe". Nature. 456 (7218): 98–101. doi:10.1038/nature07331. ISSN 0028-0836. PMC 2735096. Archived from the original on 2024-12-12.
  12. ^ Tian C, Kosoy R, Nassir R, Lee A, Villoslada P, Klareskog L, et al. (2009). "European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups". Molecular Medicine. 15 (11–12): 371–383. doi:10.2119/molmed.2009.00094. PMC 2730349. PMID 19707526.
  13. ^ «Sicily and Southern Italy were heavily colonized by Greeks beginning in the eight to ninth century B.C.. The demographic development of the Greek colonies in Southern Italy was remarkable, and in classical times this region was called Magna Graecia (Great Greece) because it probably surpassed in numbers the Greek population of the motherland.» Cavalli-Sforza L, Menozzi P, Piazza A (1994). The History and Geography of Human Genes. Princeton University Press. p. 278. ISBN 978-0-691-08750-4.
  14. ^ Cite error: The named reference Sarno_2017 was invoked but never defined (see the help page).
  15. ^ Sarno, Stefania; Boattini, Alessio; Pagani, Luca; Sazzini, Marco; De Fanti, Sara; Quagliariello, Andrea; Gnecchi Ruscone, Guido Alberto; Guichard, Etienne; Ciani, Graziella; Bortolini, Eugenio; Barbieri, Chiara; Cilli, Elisabetta; Petrilli, Rosalba; Mikerezi, Ilia; Sineo, Luca (2017-05-16). "Ancient and recent admixture layers in Sicily and Southern Italy trace multiple migration routes along the Mediterranean". Scientific Reports. 7 (1): 1984. Bibcode:2017NatSR...7.1984S. doi:10.1038/s41598-017-01802-4. ISSN 2045-2322. PMC 5434004. PMID 28512355.
  16. ^ Drineas, Petros; Tsetsos, Fotis; Plantinga, Anna; Lazaridis, Iosif; Yannaki, Evangelia; Razou, Anna; Kanaki, Katerina; Michalodimitrakis, Manolis; Perez-Jimenez, Francisco; De Silvestro, Giustina; Renda, Maria C.; Stamatoyannopoulos, John A.; Kidd, Kenneth K.; Browning, Brian L.; Paschou, Peristera (November 2019). "Genetic history of the population of Crete". Annals of Human Genetics. 83 (6): 373–388. doi:10.1111/ahg.12328. ISSN 1469-1809. PMC 6851683. PMID 31192450.
  17. ^ a b Cite error: The named reference Peristera_2014 was invoked but never defined (see the help page).
  18. ^ a b Seldin, Michael F.; Shigeta, Russell; Villoslada, Pablo; Selmi, Carlo; Tuomilehto, Jaakko; Silva, Gabriel; Belmont, John W.; Klareskog, Lars; Gregersen, Peter K. (2006-09-15). "European Population Substructure: Clustering of Northern and Southern Populations". PLOS Genetics. 2 (9): e143. doi:10.1371/journal.pgen.0020143. ISSN 1553-7404. PMC 1564423. PMID 17044734.
  19. ^ a b Stamatoyannopoulos, George; Bose, Aritra; Teodosiadis, Athanasios; Tsetsos, Fotis; Plantinga, Anna; Psatha, Nikoletta; Zogas, Nikos; Yannaki, Evangelia; Zalloua, Pierre; Kidd, Kenneth K.; Browning, Brian L.; Stamatoyannopoulos, John; Paschou, Peristera; Drineas, Petros (8 March 2017). "Genetics of the peloponnesean populations and the theory of extinction of the medieval peloponnesean Greeks". European Journal of Human Genetics. 25 (5): 637–645. doi:10.1038/ejhg.2017.18. ISSN 1476-5438. PMC 5437898. PMID 28272534.
  20. ^ Cite error: The named reference Haak_2015 was invoked but never defined (see the help page).
  21. ^ Cite error: The named reference DiGaetano_2012 was invoked but never defined (see the help page).
  22. ^ Price AL, Butler J, Patterson N, Capelli C, Pascali VL, Scarnicci F, et al. (January 2008). "Discerning the ancestry of European Americans in genetic association studies". PLOS Genetics. 4 (1): e236. doi:10.1371/journal.pgen.0030236. PMC 2211542. PMID 18208327.
  23. ^ Nelis M, Esko T, Mägi R, Zimprich F, Zimprich A, Toncheva D, et al. (8 May 2009). "Genetic structure of Europeans: a view from the North-East". PLOS ONE. 4 (5): e5472. Bibcode:2009PLoSO...4.5472N. doi:10.1371/journal.pone.0005472. PMC 2675054. PMID 19424496.
  24. ^ a b c Cite error: The named reference Fiorito_2016 was invoked but never defined (see the help page).
  25. ^ Cite error: The named reference Sazzini_2016 was invoked but never defined (see the help page).
  26. ^ Tian, Chao; Kosoy, Roman; Nassir, Rami; Lee, Annette; Villoslada, Pablo; Klareskog, Lars; Hammarström, Lennart; Garchon, Henri-Jean; Pulver, Ann E.; Ransom, Michael; Gregersen, Peter K.; Seldin, Michael F. (2009). "European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups". Molecular Medicine (Cambridge, Mass.). 15 (11–12): 371–383. doi:10.2119/molmed.2009.00094. ISSN 1528-3658. PMC 2730349. PMID 19707526.
  27. ^ Tian, Chao; Plenge, Robert M.; Ransom, Michael; Lee, Annette; Villoslada, Pablo; Selmi, Carlo; Klareskog, Lars; Pulver, Ann E.; Qi, Lihong; Gregersen, Peter K.; Seldin, Michael F. (January 2008). "Analysis and application of European genetic substructure using 300 K SNP information". PLOS Genetics. 4 (1): e4. doi:10.1371/journal.pgen.0040004. ISSN 1553-7404. PMC 2211544. PMID 18208329.

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