Hefutoxin

Hefutoxin family
kappa-hefutoxin 1 PDB entry 1hp9[1]
Identifiers
SymbolToxin_25
PfamPF08095
InterProIPR012630
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Kappa- Hefutoxin 1 and 2 are toxins from the venom of the Asian forest black scorpion Heterometrus fulvipes with a unique structure. It blocks the potassium channels Kv1.2 and Kv1.3 and slows the activation of Kv1.3.

  1. ^ Srinivasan KN, Sivaraja V, Huys I, Sasaki T, Cheng B, Kumar TK, et al. (August 2002). "kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity". The Journal of Biological Chemistry. 277 (33): 30040–30047. doi:10.1074/jbc.M111258200. PMID 12034709.

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