Muslims, including Shia, Sunni, Ibadi and other branches, agree on the three holiest sites in Islam being the Masjid al-Haram (including the Kaaba) in Mecca; the Masjid an-Nabawi in Medina; and the Masjid Al-Aqsa in Jerusalem.
Sites associated with the Islamic prophet Muhammad, his daughter Fatima and son-in-law Ali, the respective Shia Imams descended from them and their family members (collectively referred to as Ahl al-Bayt) are considered holy by the different Shia Muslim sects. Karbala and Najaf in Iraq are two of holiest cities revered by all Shia sects. Additionally, Mashhad and Qom in Iran are two of the holiest cities to Twelver Shia, the largest Shia sect.[1][2]
Sardeg
was invoked but never defined (see the help page).