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In immunology, activation is the transition of leucocytes and other cell types involved in the immune system. On the other hand, deactivation is the transition in the reverse direction.[1] This balance is tightly regulated, since a too small degree of activation causes susceptibility to infections, while, on the other hand, a too large degree of activation causes autoimmune diseases.
- ^ Kane, Barry A.; Bryant, Katherine J.; McNeil, H. Patrick; Tedla, Nicodemus T. (2014). "Termination of immune activation: an essential component of healthy host immune responses". Journal of Innate Immunity. 6 (6): 727–738. doi:10.1159/000363449. ISSN 1662-8128. PMC 6741560. PMID 25033984.