| Jamaican vomiting sickness | |
|---|---|
| Specialty | Toxicology |
Jamaican vomiting sickness, also known as toxic hypoglycemic syndrome (THS),[1] acute ackee fruit intoxication,[2] or ackee poisoning,[1] is an acute illness caused by the toxins hypoglycin A and hypoglycin B, which are present in fruit of the ackee tree. Unripe arils contain concentrations of hypoglycin A that are 20-fold higher than those of ripe arils,[3] and can cause vomiting and even death. Some countries in the Caribbean and Western Africa experience frequent cases.[4]
- ^ a b Gordon, André (2015-01-01), Gordon, André (ed.), "Chapter 4 - Biochemistry of Hypoglycin and Toxic Hypoglycemic Syndrome", Food Safety and Quality Systems in Developing Countries, San Diego: Academic Press, pp. 47–61, doi:10.1016/b978-0-12-801227-7.00004-4, ISBN 978-0-12-801227-7, retrieved 2020-07-05
- ^ "The portal for rare diseases and orphan drugs". Retrieved 5 July 2020.
- ^ Holson, David A. (28 March 2022). Thornton, Stephen L. (ed.). "Ackee Fruit Toxicity". Medscape. WebMD LLC. Retrieved 2 July 2024.
- ^ "Jamaican vomiting sickness | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Archived from the original on 2021-06-08. Retrieved 2018-04-17.