John Hughes (neuroscientist)

John Hughes
Born (1942-01-06) 6 January 1942 (age 83)[2]
NationalityBritish
EducationKing's College London
Known forCo-discovery of enkephalins
AwardsLasker award (1978)
Fellow of the Royal Society (1993)
Scientific career
FieldsNeuroscience, Pharmacology
InstitutionsYale School of Medicine
Aberdeen University
Imperial College London
University of Cambridge
PatronsHans Kosterlitz
Doctoral studentsFiona Marshall[1]
Websitewww.wolfson.cam.ac.uk/people/professor-john-hughes

John Hughes (born 6 January 1942)[2] is a British neuroscientist who shared the 1978 Albert Lasker Award for Basic Medical Research for the discovery of met-enkephalin and leu-enkephalin.[3][4][5] This discovery demonstrated that opiate drugs exert their effects on the human brain by mimicking endogenous neurotransmitters, the opioid peptides.[6][7][8][9]

  1. ^ Marshall, Fiona (1990). Cholecystokinin/dopamine interactions in the rat basal ganglia (PhD thesis). University of Cambridge. EThOS uk.bl.ethos.386170.
  2. ^ a b Hughes, Prof. John, Who's Who 2018, A & C Black, 2017
  3. ^ "Professor John Hughes". Wolfson College, University of Cambridge. Retrieved 8 January 2017.
  4. ^ "John Hughes: Biography". The Royal Society. Retrieved 23 January 2017.
  5. ^ "Opiate receptors and enkephalins". Lasker Foundation. Retrieved 8 January 2017.
  6. ^ Goldberg, Jeff (2013). Anatomy of a Scientific Discovery: The Race to Find the Body's Own Morphine. Skyhorse Publishing. ISBN 9781626361935.
  7. ^ Freeman, Karen (8 November 1996). "Hans W. Kosterlitz, 93; Found Clues in Brain on Pain Control". The New York Times.
  8. ^ Snyder, Solomon H. (1988). "Initial Findings". In Pasternak, Gavril (ed.). The Opiate Receptors. Humana Press. p. 4. ISBN 9781607619925.
  9. ^ Frankenburg, Frances R. (2014). Brain-Robbers: How Alcohol, Cocaine, Nicotine, and Opiates Have Changed Human History. Praeger. p. 213. ISBN 9781440829314.

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