John Tyler (1790–1862) was the tenth president of the United States from 1841 to 1845.
John Tyler may also refer to:
- John Tyler Sr. (1747–1813), father of President Tyler and Governor of Virginia
- John Tyler Jr. (1819-1896), son of President Tyler and his first wife, Letitia Christian Tyler
- John Alexander Tyler (1848–1883), second son of President Tyler and his second wife, Julia Gardiner Tyler
- John Tyler (bishop) (1640–1724), Bishop of Llandaff
- John Poyntz Tyler (1862–1931), Episcopal bishop, nephew of President Tyler
- John Tyler (doctor) (1764-1841), ophthalmologist