Laffitte is a surname of French origin. Notable people with that name include:
- Hector Manuel Laffitte (born 1934), former United States federal judge
- Jacques Laffitte (1767–1844), French banker and politician
- Cabinet of Jacques Laffitte, a French government ministry of 1830–31
- Jean Laffitte (born 1952), French official in the Roman Catholic church
- Juliana Laffitte (born 1974), Argentine artist
- Louis Laffitte, pseudonym of French novelist Jean-Louis Curtis (1917–95)
- Pierre Laffitte (1823–1903), French positivist