Leland H. Hartwell | |
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Born | Los Angeles, California, U.S. | October 30, 1939
Education | California Institute of Technology Massachusetts Institute of Technology |
Known for | Cell cycle regulation |
Awards | Rosenstiel Award (1992) Genetics Society of America Medal (1994) Komen Brinker Award (1998)[1] Albert Lasker Award (1998) Massry Prize (2000) Nobel Prize in Physiology or Medicine (2001) Mendel Medal (2001) Medal of Merit (2003) |
Scientific career | |
Fields | Biology |
Institutions | Fred Hutchinson Cancer Research Center Arizona State University Biodesign Institute Amrita Vishwa Vidyapeetham |
Thesis | Studies on the induction of histidase in Bacillus subtilis (1964) |
Doctoral advisor | Boris Magasanik |
Leland Harrison "Lee" Hartwell (born October 30, 1939) is an American former president and director of the Fred Hutchinson Cancer Research Center in Seattle, Washington. He shared the 2001 Nobel Prize in Physiology or Medicine with Paul Nurse and Tim Hunt, for their discoveries of protein molecules that control the division (duplication) of cells.[2]
Working in yeast, Hartwell identified the fundamental role of checkpoints in cell cycle control, and CDC genes such as CDC28, which controls the start of the cycle—the progression through G1.[2]