Protein family
Margatoxin (MgTX) is a peptide that selectively inhibits Kv1.3 voltage-dependent potassium channels. It is found in the venom of Centruroides margaritatus, also known as the Central American Bark Scorpion. Margatoxin was first discovered in 1993. It was purified from scorpion venom and its amino acid sequence was determined.
- ^ Johnson BA, Stevens SP, Williamson JM (December 1994). "Determination of the three-dimensional structure of margatoxin by 1H, 13C, 15N triple-resonance nuclear magnetic resonance spectroscopy". Biochemistry. 33 (50): 15061–70. doi:10.1021/bi00254a015. PMID 7999764.