Mercury poisoning | |
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Other names | Mercury toxicity, mercury overdose, mercury intoxication, hydrargyria, mercurialism |
The bulb of a mercury-in-glass thermometer | |
Specialty | Toxicology |
Symptoms | Muscle weakness, poor coordination, numbness in the hands and feet[1] |
Complications | Kidney problems, decreased intelligence[2] |
Causes | Exposure to mercury[1] |
Risk factors | Consumption of fish, which may contain mercury[3] |
Diagnostic method | Difficult[3] |
Prevention | Decreasing use of mercury, low mercury diet[4] |
Medication | Acute poisoning: dimercaptosuccinic acid (DMSA), dimercaptopropane sulfonate (DMPS)[5] |
Mercury poisoning is a type of metal poisoning due to exposure to mercury.[3] Symptoms depend upon the type, dose, method, and duration of exposure.[3][4] They may include muscle weakness, poor coordination, numbness in the hands and feet, skin rashes, anxiety, memory problems, trouble speaking, trouble hearing, or trouble seeing.[1] High-level exposure to methylmercury is known as Minamata disease.[2] Methylmercury exposure in children may result in acrodynia (pink disease) in which the skin becomes pink and peels.[2] Long-term complications may include kidney problems and decreased intelligence.[2] The effects of long-term low-dose exposure to methylmercury are unclear.[6]
Forms of mercury exposure include metal, vapor, salt, and organic compound.[3] Most exposure is from eating fish, amalgam-based dental fillings, or exposure at a workplace.[3] In fish, those higher up in the food chain generally have higher levels of mercury, a process known as biomagnification.[3] Less commonly, poisoning may occur as a method of attempted suicide.[3] Human activities that release mercury into the environment include the burning of coal and mining of gold.[4][7] Tests of the blood, urine, and hair for mercury are available but do not relate well to the amount in the body.[3]
Prevention includes eating a diet low in mercury, removing mercury from medical and other devices, proper disposal of mercury, and not mining further mercury.[4][2] In those with acute poisoning from inorganic mercury salts, chelation with either dimercaptosuccinic acid (DMSA) or dimercaptopropane sulfonate (DMPS) appears to improve outcomes if given within a few hours of exposure.[5] Chelation for those with long-term exposure is of unclear benefit.[5] In certain communities that survive on fishing, rates of mercury poisoning among children have been as high as 1.7 per 100.[4]