Back Insnoering van Ranvier Afrikaans عقد رانفييه Arabic Прищъпване на Ранвие Bulgarian Ranvierov čvor BS Nòdul de Ranvier Catalan گرێی ڕانڤیە CKB Ranvierovy zářezy Czech Ranviersk indsnøring Danish Ranvier-Schnürring German Nodo de Ranvier Spanish
| Node of Ranvier | |
|---|---|
 Drawing of a peripheral nerve axon (labeled "axis cylinder"), showing a node of Ranvier along with other features | |
 Nodes of Ranvier | |
| Details | |
| System | Nervous system |
| Location | Myelinated axon of a nerve |
| Identifiers | |
| Latin | incisura myelini |
| MeSH | D011901 |
| TH | H2.00.06.2.03015 |
| Anatomical terms of microanatomy | |
Nodes of Ranvier (/ˈrɑːnvieɪ/ RAHN-vee-ay),[1][2] also known as myelin-sheath gaps, occur along a myelinated axon where the axolemma is exposed to the extracellular space. Nodes of Ranvier are uninsulated axonal domains that are highly enriched in sodium and potassium ion channels complexed with cell adhesion molecules, allowing them to participate in the exchange of ions required to regenerate the action potential.[3] Nerve conduction in myelinated axons is referred to as saltatory conduction (from Latin saltus 'leap, jump') due to the manner in which the action potential seems to "jump" from one node to the next along the axon. This results in faster conduction of the action potential. The nodes of Ranvier are present in both the peripheral and central nervous systems.
- ^ "node of Ranvier". Lexico UK English Dictionary. Oxford University Press. Archived from the original on October 16, 2021.
- ^ "node of Ranvier". Merriam-Webster.com Dictionary. Merriam-Webster.
- ^ Poliak, Sebastian (2003). "The local differentiation of myelinated axons at nodes of Ranvier". Nature Reviews Neuroscience. 4 (12): 968–980. doi:10.1038/nrn1253. PMID 14682359.