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General | |
---|---|
Symbol | 18O |
Names | oxygen-18, 18O, O-18, Ω, Heavy oxygen |
Protons (Z) | 8 |
Neutrons (N) | 10 |
Nuclide data | |
Natural abundance | 0.2% |
Half-life (t1/2) | stable |
Isotope mass | 17.9991610 Da |
Spin | 0 |
Isotopes of oxygen Complete table of nuclides |
Oxygen-18 (18
O, Ω[1]) is a natural, stable isotope of oxygen and one of the environmental isotopes.
18
O is an important precursor for the production of fluorodeoxyglucose (FDG) used in positron emission tomography (PET). Generally, in the radiopharmaceutical industry, enriched water (H
2Ω) is bombarded with hydrogen ions in either a cyclotron or linear accelerator, producing fluorine-18. This is then synthesized into FDG and injected into a patient. It can also be used to make an extremely heavy version of water when combined with tritium (hydrogen-3): 3
H
218
O or T
2Ω. This compound has a density almost 30% greater than that of natural water.[2]
The accurate measurements of 18
O rely on proper procedures of analysis, sample preparation and storage.[3]