Back بروتين القفيصة P24 Arabic Proteína de la cápside vírica P24 Spanish Virus de l'immunodéficience humaine#Structure French P24 (HIV) Italian Proteína p24 Portuguese
The p24 capsid protein is the most abundant HIV protein with each virus containing approximately 1,500 to 3,000 p24 molecules.[1] It is the major structural protein within the capsid, and it is involved in maintaining the structural integrity of the virus and facilitating various stages of the viral life cycle, including viral entry into host cells and the release of new virus particles.[2] Detection of p24 protein's antigen can be used to identify the presence of HIV in a person's blood and diagnose HIV/AIDS, however, more modern tests have taken their place.[3] After approximately 50 days of infection, the p24 antigen is often cleared from the bloodstream entirely.[4]
- ^ Summers MF, Henderson LE, Chance MR, Bess JW, South TL, Blake PR, et al. (May 1992). "Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1". Protein Science. 1 (5): 563–574. doi:10.1002/pro.5560010502. PMC 2142235. PMID 1304355.
- ^ Rossi E, Meuser ME, Cunanan CJ, Cocklin S (January 2021). "Structure, Function, and Interactions of the HIV-1 Capsid Protein". Life. 11 (2): 100. Bibcode:2021Life...11..100R. doi:10.3390/life11020100. PMC 7910843. PMID 33572761.
- ^ Larijani MS, Sadat SM, Bolhassani A, Pouriayevali MH, Bahramali G, Ramezani A (2019). "In Silico Design and Immunologic Evaluation of HIV-1 p24-Nef Fusion Protein to Approach a Therapeutic Vaccine Candidate". Current HIV Research. 16 (5): 322–337. doi:10.2174/1570162x17666190102151717. PMC 6446525. PMID 30605062.
- ^ Hurt CB, Nelson JA, Hightow-Weidman LB, Miller WC (December 2017). "Selecting an HIV Test: A Narrative Review for Clinicians and Researchers". Sexually Transmitted Diseases. 44 (12): 739–746. doi:10.1097/OLQ.0000000000000719. PMC 5718364. PMID 29140890.