POLR1D

POLR1D
Identifiers
Aliases	POLR1D, AC19, POLR1C, RPA16, RPA9, RPAC2, RPC16, RPO1-3, TCS2, polymerase (RNA) I subunit D, RNA polymerase I subunit D, RNA polymerase I and III subunit D
External IDs	OMIM: 613715; MGI: 108403; HomoloGene: 22239; GeneCards: POLR1D; OMA:POLR1D - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	27,744,237 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	147,111,597 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; secondary oocyte; ; skin of abdomen; ; body of stomach; ; cerebellar hemisphere; ; right adrenal cortex; ; right hemisphere of cerebellum; ; left ovary; ; left adrenal cortex; ; right testis;
	Top expressed in
	facial motor nucleus; ; temporal muscle; ; sternocleidomastoid muscle; ; yolk sac; ; triceps brachii muscle; ; digastric muscle; ; salivary gland; ; embryo; ; submandibular gland; ; lacrimal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein dimerization activity; RNA polymerase III activity; DNA-directed 5'-3' RNA polymerase activity; protein binding; RNA polymerase I activity;
Cellular component	cytosol; nucleoplasm; RNA polymerase I complex; RNA polymerase III complex; nucleus;
Biological process	termination of RNA polymerase I transcription; epigenetic maintenance of chromatin in transcription-competent conformation; transcription initiation from RNA polymerase I promoter; transcription, DNA-templated; transcription elongation from RNA polymerase I promoter; positive regulation of type I interferon production; transcription by RNA polymerase III;
	Sources:Amigo / QuickGO
Orthologs
	51082
	20018
	ENSG00000186184
	ENSMUSG00000029642
	P0DPB5
	P97304
	NM_001206559; NM_015972; NM_152705; NM_001374407
	NM_009087; NM_181730
	NP_001193488; NP_057056; NP_689918; NP_001361336
	NP_033113; NP_859419
	Wikidata
View/Edit Human	View/Edit Mouse

DNA-directed RNA polymerases I and III subunit RPAC2 is a protein that in humans is encoded by the POLR1D gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186184 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029642 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Oct 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Research. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
^ Hu P, Wu S, Sun Y, Yuan CC, Kobayashi R, Myers MP, Hernandez N (Nov 2002). "Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits" (PDF). Molecular and Cellular Biology. 22 (22): 8044–55. doi:10.1128/MCB.22.22.8044-8055.2002. PMC 134740. PMID 12391170.
^ "Entrez Gene: POLR1D polymerase (RNA) I polypeptide D, 16kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000186184 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029642 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11042152-5] Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Oct 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Research. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.

[pmid12391170-6] Hu P, Wu S, Sun Y, Yuan CC, Kobayashi R, Myers MP, Hernandez N (Nov 2002). "Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits" (PDF). Molecular and Cellular Biology. 22 (22): 8044–55. doi:10.1128/MCB.22.22.8044-8055.2002. PMC 134740. PMID 12391170.

[entrez-7] "Entrez Gene: POLR1D polymerase (RNA) I polypeptide D, 16kDa".

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POLR1D

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