Plasmodium ovale

Plasmodium ovale
Plasmodium ovale trophozoite, Giemsa stain.
Scientific classification Edit this classification
Domain: Eukaryota
Clade: Diaphoretickes
Clade: SAR
Clade: Alveolata
Phylum: Apicomplexa
Class: Aconoidasida
Order: Haemospororida
Family: Plasmodiidae
Genus: Plasmodium
Species:
P. ovale
Binomial name
Plasmodium ovale
Stephens, 1922

Plasmodium ovale is a species of parasitic protozoon that causes tertian malaria in humans. It is one of several species of Plasmodium parasites that infect humans, including Plasmodium falciparum and Plasmodium vivax which are responsible for most cases of malaria in the world. P. ovale is rare compared to these two parasites, and substantially less dangerous than P. falciparum.

P. ovale has recently been shown by genetic methods to consist of two species, the "classic" P. ovalecurtisi and the "variant" P. ovalewallikeri (split by Sutherland et al. 2010, names amended to binomials by Snounou et al. 2024).[1][2] Depending on the type locality of the original P. ovale defined by Stephens, one of the proposed species (likely P. ovalecurtisi) may end up as a junior synonym of the old name.[3] There is a statistically significant difference between the clinicalparameters found in patients infected with either kind.[4]

  1. ^ Sutherland CJ, Tanomsing N, Nolder D, Oguike M, Jennison C, Pukrittayakamee S, et al. (May 2010). "Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally". The Journal of Infectious Diseases. 201 (10): 1544–50. doi:10.1086/652240. PMID 20380562.
  2. ^ Snounou, G; Sharp, PM; Culleton, R (January 2024). "The two parasite species formerly known as Plasmodium ovale". Trends in parasitology. 40 (1): 21–27. doi:10.1016/j.pt.2023.11.004. PMID 38040603.
  3. ^ Šlapeta, Jan; Sutherland, Colin J.; Fuehrer, Hans-Peter (March 2024). "Calling them names: variants of Plasmodium ovale". Trends in Parasitology. 40 (3): 205–206. doi:10.1016/j.pt.2023.12.010.
  4. ^ Mahittikorn, Aongart; Masangkay, Frederick Ramirez; Kotepui, Kwuntida Uthaisar; Milanez, Giovanni De Jesus; Kotepui, Manas (2021-03-19). "Comparison of Plasmodium ovale curtisi and Plasmodium ovale wallikeri infections by a meta-analysis approach". Scientific Reports. 11 (1). doi:10.1038/s41598-021-85398-w. PMC 7979700.

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