| Porcine circovirus | |
|---|---|
| |
Scientific classification
| |
| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cressdnaviricota |
| Class: | Arfiviricetes |
| Order: | Cirlivirales |
| Family: | Circoviridae |
| Genus: | Circovirus |
| Groups included | |
| Cladistically included but traditionally excluded taxa | |
|
(See Circovirus) | |
Porcine circovirus (PCV) is a group of four[1] single-stranded DNA viruses that are non-enveloped with an unsegmented circular genome. They are members of the genus Circovirus that can infect pigs.[2] The viral capsid is icosahedral and approximately 17 nm in diameter.
PCVs are the smallest viruses replicating autonomously in eukaryotic cells.[3] They replicate in the nucleus of infected cells, using the host polymerase for genome amplification.
PCV-2 causes Porcine circovirus associated disease or postweaning multisystemic wasting syndrome (PMWS). An effective vaccination is now available. Fort Dodge Animal Health (Wyeth) launched the first USDA approved vaccine in 2006, containing an inactivated virus (ATCvet code: QI09AA07 (WHO)).[2]
- ^ "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved May 11, 2021.
- ^ a b Ellis, J (March 2014). "Porcine circovirus: a historical perspective". Veterinary Pathology. 51 (2): 315–327. doi:10.1177/0300985814521245. PMID 24569612. S2CID 1406680.
- ^ Mankertz P (2008). "Molecular Biology of Porcine Circoviruses". Animal Viruses: Molecular Biology. Caister Academic Press. ISBN 978-1-904455-22-6.