Pradofloxacin

Pradofloxacin
Clinical data
Trade names	Veraflox, Pradalex
License data	US DailyMed: Pradofloxacin;
Routes of; administration	By mouth, intramuscular, subcutaneous
ATCvet code	QJ01MA97 (WHO) ;
Legal status
Legal status	CA: ℞-only; US: ℞-only; EU: Rx-only;
Identifiers
	IUPAC name 8-Cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-(4.3.0)nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid;
CAS Number	195532-12-8 ;
PubChem CID	9802884;
ChemSpider	7978646 ;
UNII	6O0T5E048I;
CompTox Dashboard (EPA)	DTXSID60173229 ;
ECHA InfoCard	100.169.611
Chemical and physical data
Formula	C21H21FN4O3
Molar mass	396.422 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)C1=CN(C2CC2)c3c(C1=O)cc(F)c(c3C#N)N4C[C@H]5NCCC[C@H]5C4;
	InChI InChI=1S/C21H21FN4O3/c22-16-6-13-18(26(12-3-4-12)9-15(20(13)27)21(28)29)14(7-23)19(16)25-8-11-2-1-5-24-17(11)10-25/h6,9,11-12,17,24H,1-5,8,10H2,(H,28,29)/t11-,17+/m0/s1 ; Key:LZLXHGFNOWILIY-APPDUMDISA-N ;
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Pradofloxacin, sold under the brand name Veraflox among others, is a third-generation enhanced spectrum veterinary antibiotic of the fluoroquinolone class.^[5] It was developed by Elanco Animal Health GmbH and received approval from the European Commission in April 2011, for prescription-only use in veterinary medicine for the treatment of bacterial infections in dogs and cats.^[6]^[7]

^ "Veraflox Product information". Health Canada. 19 May 2022. Retrieved 12 April 2024.
^ "Veraflox- pradofloxacin suspension". DailyMed. 14 October 2022. Retrieved 12 April 2024.
^ "Pradalex (pradofloxacin injection) Injectable Solution". New Animal Drug Application. U.S. Food and Drug Administration. NADA 141-550.
^ "Veraflox EPAR". European Medicines Agency. 12 April 2011. Retrieved 12 April 2024.
^ Cite error: The named reference FDA Pradalex was invoked but never defined (see the help page).
^ "Veraflox Product information". Union Register of veterinary medicinal products. Retrieved 20 June 2012.
^ Sykes JE, Blondeau JM (August 2014). "Pradofloxacin: a novel veterinary fluoroquinolone for treatment of bacterial infections in cats". Veterinary Journal. 201 (2). London, England: 207–14. doi:10.1016/j.tvjl.2014.06.008. PMID 24997792.

[1] "Veraflox Product information". Health Canada. 19 May 2022. Retrieved 12 April 2024.

[Veraflox_FDA_label-2] "Veraflox- pradofloxacin suspension". DailyMed. 14 October 2022. Retrieved 12 April 2024.

[3] "Pradalex (pradofloxacin injection) Injectable Solution". New Animal Drug Application. U.S. Food and Drug Administration. NADA 141-550.

[4] "Veraflox EPAR". European Medicines Agency. 12 April 2011. Retrieved 12 April 2024.

[FDA_Pradalex-5] Cite error: The named reference FDA Pradalex was invoked but never defined (see the help page).

[Europa-6] "Veraflox Product information". Union Register of veterinary medicinal products. Retrieved 20 June 2012.

[pmid24997792-7] Sykes JE, Blondeau JM (August 2014). "Pradofloxacin: a novel veterinary fluoroquinolone for treatment of bacterial infections in cats". Veterinary Journal. 201 (2). London, England: 207–14. doi:10.1016/j.tvjl.2014.06.008. PMID 24997792.

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Pradofloxacin

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