Back Piridoksien Afrikaans بيريدوكسين Arabic Piridoksin Azerbaijani Пірыдаксін Byelorussian Пиридоксин Bulgarian পাইরিডক্সিন Bengali/Bangla Piridoxina Catalan Pyridocsin Welsh Pyridoxin German Πυριδοξίνη Greek
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 Pyridoxine | |
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| Other names | vitamin B6, pyridoxol[1] pyridoxine hydrochloride |
| AHFS/Drugs.com | Monograph |
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| Routes of administration | By mouth, intravenous (IV), intramuscular (IM), subcutaneous |
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| Pharmacokinetic data | |
| Elimination half-life | several weeks (see #Metabolism for details) |
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| ECHA InfoCard | 100.000.548 |
| Chemical and physical data | |
| Formula | C8H11NO3 |
| Molar mass | 169.180 g·mol−1 |
| 3D model (JSmol) | |
| Melting point | 159 to 162 °C (318 to 324 °F) |
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Pyridoxine (PN)[4] is a form of vitamin B6 found commonly in food and used as a dietary supplement. As a supplement it is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning.[5] It is used by mouth or by injection.[5]
It is usually well tolerated.[5] Occasionally side effects include headache, numbness, and sleepiness.[5] Normal doses are safe during pregnancy and breastfeeding.[5] Pyridoxine is in the vitamin B family of vitamins.[5] It is required by the body to metabolise amino acids, carbohydrates, and lipids.[5] Sources in the diet include meat, fish, fruit, vegetables, and grain.[6]
- ^ Dryhurst G (2012). "Electrochemistry of Biologically Important Pyridines". Electrochemistry of Biological Molecules. Elsevier. p. 562. ISBN 978-0-323-14452-0. Archived from the original on 30 December 2016.
- ^ "Pyridoxine Use During Pregnancy". Drugs.com. 27 April 2020. Archived from the original on 4 December 2020. Retrieved 6 May 2020.
- ^ "Pyridoxine 50mg Tablets - Summary of Product Characteristics (SmPC)". (emc). 27 April 2015. Archived from the original on 12 October 2013. Retrieved 6 May 2020.
- ^ "Vitamin B-6". iupac.qmul.ac.uk. Retrieved 26 September 2024.
- ^ a b c d e f g "Pyridoxine Hydrochloride". The American Society of Health-System Pharmacists. Archived from the original on 30 December 2016. Retrieved 8 December 2016.
- ^ "Office of Dietary Supplements - Dietary Supplement Fact Sheet: Vitamin B6". ods.od.nih.gov. 11 February 2016. Archived from the original on 12 December 2016. Retrieved 30 December 2016.