Back Rustelosebenesindroom Afrikaans متلازمة تململ الساقين Arabic Narahat ayaqlar sindromu Azerbaijani ناراحات آیاقلار سیندرومو AZB Síndrome de les cames inquietes Catalan Restless legs syndrome Danish Restless-Legs-Syndrom German Σύνδρομο ανήσυχων ποδιών Greek Síndrome de las piernas inquietas Spanish Rahutute jalgade sündroom Estonian

Restless legs syndrome

"Restless legs" redirects here. For the song by Half Man Half Biscuit, see Achtung Bono.
Restless legs syndrome
Other namesWillis–Ekbom disease (WED),[1] Wittmaack–Ekbom syndrome
Sleep pattern of a person with restless legs syndrome (red) compared to a healthy sleep pattern (blue)
SpecialtySleep medicine
SymptomsUnpleasant feeling in the legs that briefly improves with moving them[2]
ComplicationsDaytime sleepiness, low energy, irritability, sadness[2]
Usual onsetMore common with older age[3]
Risk factorsLow iron levels, kidney failure, Parkinson's disease, diabetes mellitus, rheumatoid arthritis, pregnancy, certain medications[2][4][5]
Diagnostic methodBased on symptoms after ruling out other possible causes[6]
TreatmentLifestyle changes, medication[2]
MedicationDopamine agonists, levodopa, gabapentinoids, opioids[4][7][8][9]
Frequency2.5–15% (US)[4]

Restless legs syndrome (RLS), (also known as Willis–Ekbom disease (WED), is a neurological disorder, usually chronic, that causes an overwhelming urge to move one's legs.[2][10] There is often an unpleasant feeling in the legs that improves temporarily by moving them.[2] This feeling is often described as aching, tingling, or crawling in nature.[2] Occasionally, arms may also be affected.[2] The feelings generally happen when at rest and therefore can make it hard to sleep.[2] Sleep disruption may leave people with RLS sleepy during the day, with low energy, and irritable or depressed.[2] Additionally, many have limb twitching during sleep, a condition known as periodic limb movement disorder.[11] RLS is not the same as habitual foot-tapping or leg-rocking.[12]

  1. ^ "Restless Legs Syndrome Fact Sheet | National Institute of Neurological Disorders and Stroke". Ninds.nih.gov. Archived from the original on 28 July 2017. Retrieved 7 July 2019.
  2. ^ a b c d e f g h i j "What Is Restless Legs Syndrome?". NHLBI. November 1, 2010. Archived from the original on 21 August 2016. Retrieved 19 August 2016.
  3. ^ Cite error: The named reference NIH2010Age was invoked but never defined (see the help page).
  4. ^ a b c Cite error: The named reference AFP2013 was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference NIH2010Ca was invoked but never defined (see the help page).
  6. ^ Cite error: The named reference NIH2010Diag was invoked but never defined (see the help page).
  7. ^ Cite error: The named reference pmid27448465 was invoked but never defined (see the help page).
  8. ^ Cite error: The named reference pmid34218864 was invoked but never defined (see the help page).
  9. ^ Gossard, Thomas R.; Trotti, Lynn Marie; Videnovic, Aleksandar; St Louis, Erik K. (20 April 2021). "Restless Legs Syndrome: Contemporary Diagnosis and Treatment" (PDF). Neurotherapeutics. 18 (1): 140–155. doi:10.1007/s13311-021-01019-4. PMC 8116476. PMID 33880737. Archived (PDF) from the original on 27 January 2023. Retrieved 27 January 2023.
  10. ^ "Restless Legs Syndrome Information Page | National Institute of Neurological Disorders and Stroke". Ninds.nih.gov. Archived from the original on 8 October 2019. Retrieved 7 July 2019.
  11. ^ "What Are the Signs and Symptoms of Restless Legs Syndrome?". NHLBI. November 1, 2010. Archived from the original on 27 August 2016. Retrieved 19 August 2016.
  12. ^ Cite error: The named reference :5 was invoked but never defined (see the help page).
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