STFC can stand for:
- Science and Technology Facilities Council, a UK research council created by the merger of the Council for the Central Laboratory of the Research Councils (CCLRC) and the Particle Physics and Astronomy Research Council (PPARC) on 1 April 2007
- Star Trek: First Contact, a 1996 film
- Star Trek Fleet Command, a 2018 video game
STFC also stands for the names of many football clubs, most notably the professional clubs
It may also refer to one of the following other clubs:
In China:
In England:
- Sandhurst Town F.C.
- Sandiacre Town F.C.
- Sawbridgeworth Town F.C.
- Seaford Town F.C.
- Selby Town F.C.
- Sevenoaks Town F.C.
- Shefford Town F.C.
- Sherborne Town F.C.
- Shifnal Town F.C.
- Shirebrook Town F.C.
- Sleaford Town F.C.
- Slough Town F.C.
- Somersham Town F.C.
- Spennymoor Town F.C.
- Stafford Town F.C.
- Staines Town F.C.
- Steyning Town F.C.
- Stockport Town F.C.
- Stonehouse Town F.C.
- Stowmarket Town F.C.
- Stratford Town F.C.
- Swaffham Town F.C.
In Scotland: