Back موصل محكم Arabic Unió estreta Catalan Tight Junction German Zonula occludens Spanish Lotura estua (zelula) Basque اتصالات محکم Persian Tiivis liitos Finnish Jonction serrée French Unión hermética Galician Sambungan ketat ID
| Tight junction | |
|---|---|
 Diagram of tight junction | |
| Details | |
| Identifiers | |
| Latin | junctio occludens |
| MeSH | D019108 |
| TH | H1.00.01.1.02007 |
| FMA | 67397 |
| Anatomical terminology | |
Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens), are multiprotein junctional complexes between epithelial cells,[1], sealing and preventing leakage of solutes and water. They also play a critical role maintaining the structure and permeability of endothelial cells.[1] Tight junctions may also serve as leaky pathways by forming selective channels for small cations, anions, or water. The corresponding junctions that occur in invertebrates are septate junctions.
- ^ a b Bhat, Ajaz A.; Uppada, Srijayaprakash; Achkar, Iman W.; Hashem, Sheema; Yadav, Santosh K.; Shanmugakonar, Muralitharan; Al-Naemi, Hamda A.; Haris, Mohammad; Uddin, Shahab (2019). "Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk". Frontiers in Physiology. 9: 1942. doi:10.3389/fphys.2018.01942. ISSN 1664-042X. PMC 6351700. PMID 30728783.