Segment of American highway
This article is about the section of U.S. Route 50 in Ohio. For the entire route, see
U.S. Route 50.
U.S. Route 50 (US 50) runs east–west across the southern part of the state of Ohio, passing through Cincinnati, Chillicothe, and Athens. It is mainly a two-lane road except for the easternmost and westernmost parts. Near Athens it runs concurrently with State Route 32 (SR 32), a four-lane divided highway known as Corridor D, and from Coolville to the Ohio–West Virginia border it also overlaps SR 7 before crossing into Parkersburg, West Virginia.