William Trent (1715–1787) was an American fur trader and merchant.
William Trent may also refer to:
- William Trent (Trenton) (c. 1653–1724), founder of Trenton, New Jersey
- William Peterfield Trent (1862–1939), American academic
- William Edward Trent (1874–1948), British architect
- William J. Trent (1910–1993), African-American economist, non-profit director and civil rights activist