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| Xylose isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 D-Xylose isomerase tetramer from Streptomyces rubiginosus PDB 2glk.[1] One monomer is coloured by secondary structure to highlight the TIM barrel architecture. | |||||||||
| Identifiers | |||||||||
| EC no. | 5.3.1.5 | ||||||||
| CAS no. | 9023-82-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a xylose isomerase (EC 5.3.1.5) is an enzyme that catalyzes the interconversion of D-xylose and D-xylulose. This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The isomerase has now been observed in nearly a hundred species of bacteria.[2] Xylose-isomerases are also commonly called glucose isomerase or fructose isomerases due to their ability to interconvert glucose and fructose. The systematic name of this enzyme class is α-D-xylopyranose aldose-ketose-isomerase. Other names in common use include D-xylose isomerase, D-xylose ketoisomerase, and D-xylose ketol-isomerase.[3]
- ^ Katz AK, Li X, Carrell HL, Hanson BL, Langan P, Coates L, et al. (May 2006). "Locating active-site hydrogen atoms in D-xylose isomerase: time-of-flight neutron diffraction". Proceedings of the National Academy of Sciences of the United States of America. 103 (22): 8342–8347. Bibcode:2006PNAS..103.8342K. doi:10.1073/pnas.0602598103. PMC 1482496. PMID 16707576.
- ^ Xiao H, Gu Y, Ning Y, Yang Y, Mitchell WJ, Jiang W, et al. (November 2011). "Confirmation and elimination of xylose metabolism bottlenecks in glucose phosphoenolpyruvate-dependent phosphotransferase system-deficient Clostridium acetobutylicum for simultaneous utilization of glucose, xylose, and arabinose". Applied and Environmental Microbiology. 77 (22): 7886–7895. Bibcode:2011ApEnM..77.7886X. doi:10.1128/AEM.00644-11. PMC 3208996. PMID 21926197.
- ^ Mu W, Hassanin HA, Zhou L, Jiang B (December 2018). "Chemistry Behind Rare Sugars and Bioprocessing". Journal of Agricultural and Food Chemistry. 66 (51): 13343–13345. doi:10.1021/acs.jafc.8b06293. PMID 30543101. S2CID 56145019.