Yakutsk is the capital of the Sakha Republic, Russia.
Yakutsk may also refer to:
- Yakutsk Urban Okrug, a municipal formation in the Sakha Republic, Russia, which the city of Yakutsk and eleven rural localities in its jurisdiction are incorporated as
- Yakutsk Airport, an airport in the Sakha Republic, Russia
- Yakutsk Time, a time zone in Russia, ten hours ahead of UTC
- Asia/Yakutsk, a time zone identifier in the Tz database
- Yakutsk constituency, Russian legislative constituency
- Yakutsk electoral district (Russian Constituent Assembly election, 1917)