Receptorii GABA subtypus A est receptorium ionotropicum.
Receptoria GABA sunt grex receptoriorum neurotransmissoris, quae in vertebratorum systemate nervoso centrali ab neurotransmissore inhibente GABA stimulantur[1]. Adhuc tres classes inventae sunt: Receptoria GABAA ac receptoria GABAA-ρ ionotropicae enim et receptoria GABAB proteino G copulata. Nimirum velocitates eorundem divertunt: Cum ionotropica celeriora essent, ita proteino G copulatum GABAB tardius est.
Per receptoria GABA in vertebratorum systemate nervoso centrali operationes inhibentes principales[2] excellunt.
Praeterea receptoriis GABA in iecoris hepatocytis quoque et cholangiocytis ductūs biliaris[3] functiones enim, velut in pancreate[4], sunt.
Acidum γ-aminobutyricum, "GABA" abbreviatum
- ↑ Watanabe M., Maemura K., Kanbara K., Tamayama T., Hayasaki H. (2002). "GABA and GABA receptors in the central nervous system and other organs". International Revue of Cytology 213: 1-47
- ↑ Olsen R. W., Tobin A. J. (1990). "Molecular biology of GABAA receptors". FASEB journal 4 (5): 1469-80
- ↑ Wang S., Zhang L., Liu C., Lu W. Y. (2017). "Protective roles of hepatic GABA signaling in liver injury". International journal of physiology, pathophysiology and pharmacology 9 (5): 153-6
- ↑ Dong H., Kumar M., Zhang Y., Gyulkhandanyan A., Xiang Y. Y., Ye B., Perrella J., Hyder A., Zhang N., Wheeler M., Lu W. Y., Wang Q. (2006). "Gamma-aminobutyric acid up- and downregulates insulin secretion from beta cells in concert with changes in glucose concentration". Diabetologia 49 (4): 697-705